How does it work
Meloxicam can be used to reduce inflammation and pain that is caused by various injuries, medical conditions, or even surgery.
Meloxicam is a drug that blocks the actions of the enzymes called cyclooxygenase (COX)-1 and COX-2 which block prostaglandin production. Prostaglandins increase the body temperature and make nerve endings more prone to the transmission of pain.
Meloxicam is part of a class of drugs that are referred to as NSAIDs (nonsteroidal anti-inflammatory medications).
Effective in the treatment of inflammation and pain that is caused by osteoarthritis and Rheumatoid arthritis.
Can be used to help treat headaches, menstrual cramps, and colds. It can also be used to treat flu-like symptoms.
NSAIDs (including meloxicam) are considered to be the first line of treatment for moderate to mild arthritis as long as they are taken in the correct doses. are safe, don’t create dependence, and are available at a reasonable cost.
Helps reduce inflammation and pain.
They are available as a single drug and some can be combined with other medicines.
Can be taken either with or without food.
Available in the form of oral tablets, capsules as well as a suspension. The suspension and tablets are bio-equivalent. The suspension is recommended for children with a weight of less than 60kg, as it is simpler to determine the dose.
Adjusting dosage is not required for moderate to mild hepatic or kidney impairment. It has not been researched for patients with severe kidney or liver disease.
Generic meloxicam is now available.
If you’re between the ages of 18 and 60 and you do not take any other medications or suffer from any other medical issues, the possible side effects that you will likely experience are:
Indigestion, stomach-related side effects bleeding, heartburn, and indigestion. Flatulence, constipation, diarrhea nausea, vomiting, or bleeding could also occur. Patients who are elderly and taking other medications that affect their stomachs or who drink more than three glasses of alcohol per day are more likely to be at risk of developing side adverse effects, which include stomach-related. Meloxicam is believed to be safe for stomach-related side effects, compared to other NSAIDs.
Many NSAIDs have been linked with a higher chance of having a stroke or heart attack. The risk could be greater for those with existing cardiovascular problems and greater doses. NSAID usage can cause or increase the risk of high blood pressure or increase the chance of being hospitalized in the event of heart failure.
It may not be appropriate for certain people, including people with kidney diseases or the presence of stomach ulcers or other digestive conditions, pre-existing cardiovascular diseases, or a history of repeated heart attacks. Don’t give it to patients who have recently undergone coronary bypass graft surgery.
The liver enzymes can increase as much as three times. A fatal liver injury is not common. In the long run, prolonged use can damage kidneys. Patients are advised to be watched for signs of an increase in kidney function. The increase in potassium levels could be a sign of a problem.
It is not a substitute for aspirin to prevent heart attacks.
It may interact with other medications, such as warfarin, SSRIs ACE inhibitors, and diuretics.
NSAIDs, like meloxicam, should not be taken during the last 3 months of pregnancy since they may cause early closure of the embryonic arteriosus ductus. Furthermore that the use of NSAIDs around 20 weeks pregnant or later can cause fetal kidney issues that can lead to the condition known as oligohydramnios (low Amniotic Fluid Volume) and occasionally kidney damage. When NSAID treatment is recommended during the period between 20 to 30 weeks, choose the dose that is most effective for the least amount of period of. Avoid NSAIDs after 30 weeks gestation.
Not all those who are children or seniors, who suffer from certain medical conditions (such as kidney or liver problems, heart disease seizures, diabetes) or who are taking other medications are at a higher risk of experiencing a greater variety of adverse negative side adverse effects. Check out the complete list of adverse consequences
Meloxicam can be effective in the short-term relief from inflammation and pain that is associated with arthritis. However, unlike other NSAIDs, they have the potential to negatively affect the heart or stomach and can increase the tendency to bleed.
Can be taken with no taking into account meals.
Utilize the lowest dose to get the shortest amount of time.
Available as a suspension tablet or capsule.
The response to different NSAIDs may differ, so switching kinds (such as switching from meloxicam to naproxen) can improve your response.
NSAIDs shouldn’t be used in the final 3 months of pregnancy. Always consult your physician before taking medications during pregnancy. Don’t use NSAIDs, like meloxicam, for example, in the period between 20 to 30 weeks of gestation without your doctor’s guidance as it can cause kidney problems as well as reduced amniotic fluid volume in the infant. Acetaminophen is a possibility as a treatment for inflammation and pain during pregnancy.
A lot of products that combat colds and flu pain, sleep, or other disturbances could contain NSAIDs. Don’t take more than one of the NSAIDs. Always consult your physician or pharmacist to confirm that the meloxicam you take is safe alongside other medications you might be taking.
Do not use if you have any history of asthma or hives following the use of aspirin or any other NSAIDs such as ibuprofen.
Alcohol consumption in combination with alcohol can increase the chance of bleeding or stomach ulcers.
This medicine should not be used for coronary bypass surgery (CABG).
Contact a doctor right away when you have any issues in breathing, unanswered sickness or appetite loss, fatigue or vision, changes in vision or fluid retention, irregular bleeding, or other troubling adverse effects.
Response as well as the effectiveness
Peak concentrations can be reached in 2-hours (capsule) and between 4 and five hours (tablets). Meloxicam is believed to be recycled by the liver, so a second peak is achieved in eight hours (capsule) or 12-14 hours (tablet) following the dose that was taken in the beginning.
Meloxicam-related medications can either reduce its effects or alter the length of time it takes to work, create adverse effects, or produce a lesser effects when taken in conjunction with the meloxicam. The interaction between two drugs is not necessarily a sign that you have to discontinue taking the medication but sometimes it can. Consult your doctor regarding the best way to handle drug interactions. handled.
Common drugs that could be in a relationship with meloxicam are:
ACE inhibitors, or ARBs like captopril, enalapril, or losartan (monitor BP)
antibiotics, like vancomycin and ciprofloxacin.
Anticoagulants (blood thinners) such as apixaban dabigatran fondaparinux, heparin, or warfarin
antidepressants, like fluoxetine, escitalopram, citalopram, or paroxetine
antifungals, such as voriconazole
beta-blockers such as atenolol (acebutolol), acebutolol, or carvedilol
bisphosphonates, like alendronate
diuretics (water pills) diuretics (water pills) include chlorthalidone (water pills), chlorothiazide, or furosemide
HIV medicines (eg Stribild, Tenofovir, etc.)
other nonsteroidal anti-inflammatory medications (NSAIDs) like celecoxib, diclofenac, etodolac, ibuprofen, ketorolac, naproxen, or nabumetone.
Sulfonylureas (a kind that is a type of diabetic medication) like glimepiride or glyburide or the drug glipizide
supplements, like omega-3 fatty acids, glucosamine as well as vitamin E
Other examples include methotrexate, lithium, cyclosporine other drugs, including pemetrexed and pirfenidone or tacrolimus.